These headaches may be a sign that the medication is working as it should. Use of herbal products and potential interactions in patients with cardiovascular diseases. Mayo Clinic; 2021. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. 7.6 out of 10 from a total of 8.0 out of 10 from a total of Many common herbal supplements interact with common heart medicines. See also: aspirin side effects in more detail. eCollection 2021. Drug information provided by: IBM Micromedex. Some side effects may occur that usually do not need medical attention. Ask your pharmacist any questions you have about refilling your prescription. Isosorbide is in a class of medications called vasodilators. Many people using this medication do not have serious side effects. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. If you have any questions about this medicine ask your pharmacist. sharing sensitive information, make sure youre on a federal The tablet usually is taken two or three times daily. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. May also be prescribed off label for Esophageal Spasm. I strongly feel that there is coronary ischemia. To help you remember, take it at the same times each day. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. GoodRx works to make its website accessible to all, including those with disabilities. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Integrative medicine (complementary and alternative medicine). Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). Glyceryl trinitrate (GTN) is commonly prescribed for this. St. Joseph 81 mg Aspirin Enteric Safety-Coated. Which drugs or supplements interact with isosorbide mononitrate? Moderately clinically significant. This is called tolerance, and it cannot be fixed by raising the dose of the medication. Take the container with you, even if it is empty. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. This list covers only some interactions. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Federal government websites often end in .gov or .mil. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Egton Medical Information Systems Limited. Longer-acting tablets and capsules are taken once daily in the morning. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. Accessed Sept. 7, 2022. To view a report comparing 3 (or more) medications, please sign in or create an account. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . 46 ratings on Drugs.com. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? Headache and weakness of left side (both arm and leg) may suggest a brain pathology. Things to remember when you fill your prescription. View more. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Do not change the dosing times unless directed by your doctor. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Do not take more or less of it or take it more often than prescribed by your doctor. FOIA To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Evening primrose. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. you should know that you may experience headaches every day during your treatment with isosorbide. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. Yet many herbal supplements may interact with heart disease medicines. Don't drink alcohol while taking isosorbide mononitrate (Monoket). Keep this medication in the container it came in, tightly closed, and out of reach of children. This should pass after a few days. Copyright, 2023. Take the missed dose as soon as you remember it. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Saw palmetto. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Accessed Sept. 7, 2022. It will not treat an angina attack that has already begun. If you have recently had a head injury or a heart attack. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. Botanical medicine A modern perspective. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Real test is coronary angiography. The narrowing makes it more difficult for blood to flow to your heart muscle. Natural Medicines. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Unauthorized use of these marks is strictly prohibited. What special dietary instructions should I follow? Accessed Sept. 7, 2022. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Herbal medications in cardiovascular medicine. Isosorbide may cause other side effects. Some don't work well with prescription medicines. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. If it is within 2 hours of the next dose, skip the missed dose. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. View all Learn to reduce stress through mindful living. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Eur Heart J. Follow directions about how much medicine to take. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. There are 195 drugs known to interact with There may be variations in CSA schedules between individual states. Overview of herbal medicines and dietary supplements. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. This medicine is for you. information submitted for this request. Natural Medicines. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Isosorbide mononitrate: isosorbide mononitrate. See also: nitroglycerin side effects in more detail. Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. isosorbide mononitrate prices. Alcohol or marijuana (cannabis) can make you more dizzy. The extended-release tablet usually is taken once daily in the morning. Zhonghua Yi Xue Za Zhi (Taipei). Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. If you miss a dose, take it as soon as you remember. Consult your doctor for more details. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Do not share this medication with others. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Store it at room temperature and away from excess heat and moisture (not in the bathroom). 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. If you have an underactive thyroid gland. Do not stop taking it without consulting your doctor. We don't support your browser. Canada residents can call a provincial poison control center. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. Then, there was a two-week placebo washout, after which the alternative treatment was given. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. All rights reserved. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. 2005 - 2023 WebMD LLC. https://naturalmedicines.therapeuticresearch.com. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Methods: It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. You may report side effects to Health Canada at 1-866-234-2345. It is important that you follow the instructions your doctor gives to you about when to take your doses. Accessed Sept. 7, 2022. This site complies with the HONcode standard for trustworthy health information: verify here. See the full pregnancy warnings document. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). It is used to treat and prevent a wide range of different conditions. It is best not to drink alcohol while you are on isosorbide mononitrate. Take care, thanks. It is in the nitrate class of drugs. What are the interactions of Isosorbide Mononitrate ? Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. Side effects : headache, mild dizziness Please upgrade your browser or download modern browsers from here! Elsevier; 2021. https://www.clinicalkey.com. To use the sharing features on this page, please enable JavaScript. This medication belongs to a class of drugs known as nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Although not all of these side effects may occur, if they do occur they may need medical attention. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. All Rights Reserved. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. This is not a complete list of possible side effects. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). If this worries you, talk to your doctor or pharmacist about other options. MeSH So get a ct scan brain apart from cardiology workup. Do not let anyone else take your medication. Properly discard this product when it is expired or no longer needed. Some products have ingredients that could worsen your heart failure. It works by . If concomitant therapy cannot be avoided, monitor clinical effects of the . This document does not contain all possible drug interactions. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. AskMayoExpert. We study millions of patients and 5,000 more each day. health information, we will treat all of that information as protected health My EKG showed Assess your symptoms online with our free symptom checker. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Try to keep your regular appointments with your doctor. With any medication, there are risks and benefits. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. Consult your pharmacist or local waste disposal company. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Call your doctor if you have any unusual problems while you are taking this medication. May also be prescribed off label for Esophageal Spasm. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Isosorbide mononitrate. Do not stop taking isosorbide without talking to your doctor. Mayo Clinic. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. I would rather take the chance of a heart attack than have no quality of life. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. The two dosage regimens were equally efficient for the relief of angina pectoris without development of tolerance. During pregnancy, this medication should be used only when clearly needed. This medicine is available only with your doctor's prescription. https://naturalmedicines.therapeuticresearch.com. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. This risk may be even higher for certain groups. Data were assessed for carryover and time effects. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. What special precautions should I follow? It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily.